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1

Molecular Basis for β-Glucosidase Inhibition by Ring-Modified Calystegine Analogues

Matilde Aguilar, Tracey M. Gloster, M. Isabel García-Moreno, Carmen Ortiz Mellet, Gideon J. Davies, Amadeu Llebaria, Josefina Casas, Meritxell Egido-Gabás, José M. García Fernandez

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 443 KB

english, 2008

2

Chaperone Activity of Bicyclic Nojirimycin Analogues for Gaucher Mutations in Comparison with N-(n-nonyl)Deoxynojirimycin

Zhuo Luan, Katsumi Higaki, Matilde Aguilar-Moncayo, Haruaki Ninomiya, Kousaku Ohno, M. Isabel García-Moreno, Carmen Ortiz Mellet, José M. García Fernández, Yoshiyuki Suzuki

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 482 KB

english, 2009

3

ChemInform Abstract: Chemistry and Developments of N-Thiocarbonyl Carbohydrate Derivatives: Sugar Isothiocyanates, Thioamides, Thioureas, Thiocarbamates, and Their Conjugates

Jose Manuel Garcia Fernandez, Carmen Ortiz Mellet

Journal:

Année:

2000

Fichier:

PDF, 25 KB

2000

4

Stereocontrolled synthesis of sulfur-linked analogues of the branched tetrasaccharide repeating-unit of the immunostimulant polysaccharide schizophyllan and of its β-(1 → 3)-branched, β-(1 → 6)-linked isomer

Marie-Odile Contour-Galcera, Yili Ding, Carmen Ortiz-Mellet, Jacques Defaye

Journal:

Carbohydrate Research

Année:

1996

Langue:

english

Fichier:

PDF, 497 KB

english, 1996

5

Aza-Wittig reaction of sugar isothiocyanates and sugar iminophosphoranes: An easy entry to unsymmetrical sugar carbodiimides

JoséM. García Fernández, Carmen Ortiz Mellet, Víctor M. Díaz Pérez, J. Fuentes, József Kovács, István Pintér

Journal:

Tetrahedron Letters

Année:

1997

Langue:

english

Fichier:

PDF, 269 KB

english, 1997

6

Cyclodextrin-based multivalent glycodisplays: covalent and supramolecular conjugates to assess carbohydrate–protein interactions

Martínez, Álvaro, Ortiz Mellet, Carmen, García Fernández, José M.

Journal:

Chemical Society Reviews

Année:

2013

Langue:

english

Fichier:

PDF, 12.33 MB

english, 2013

7

Dynamic Self-Assembly of Polycationic Clusters Based on Cyclodextrins for pH-Sensitive DNA Nanocondensation and Delivery by Component Design

Gallego-Yerga, Laura, González-Álvarez, M. José, Mayordomo, Natalia, Santoyo-González, Francisco, Benito, Juan M., Ortiz Mellet, Carmen, Mendicuti, Francisco, García Fernández, José M.

Journal:

Chemistry - A European Journal

Année:

2014

Langue:

english

Fichier:

PDF, 960 KB

english, 2014

8

Synthesis and Evaluation of Calystegine B 2 Analogues as Glycosidase Inhibitors

García-Moreno, M. Isabel, Benito, Juan M., Ortiz Mellet, Carmen, García Fernández, José M.

Journal:

Journal of Organic Chemistry

Année:

2001

Langue:

english

Fichier:

PDF, 169 KB

english, 2001

9

Sugar Thioureas as Anion Receptors. Effect of Intramolecular Hydrogen Bonding in the Carboxylate Binding Properties of Symmetric Sugar Thioureas

Jiménez Blanco, José L., Benito, Juan M., Mellet, Carmen Ortiz, García Fernández, José M.

Journal:

Organic Letters

Année:

1999

Langue:

english

Fichier:

PDF, 54 KB

english, 1999

10

Correlations between changes in intestinal microbiota composition and performance parameters in broiler chickens

Rubio, L. A., Peinado, M. J., Ruiz, R., Suárez-Pereira, E., Ortiz Mellet, C., García Fernández, J. M.

Journal:

Journal of Animal Physiology and Animal Nutrition

Année:

2015

Langue:

english

Fichier:

PDF, 235 KB

english, 2015

11

Inhibition of type 1 fimbriae-mediated Escherichia coli adhesion and biofilm formation by trimeric cluster thiomannosides conjugated to diamond nanoparticles

Khanal, Manakamana, Larsonneur, Fanny, Raks, Victoriia, Barras, Alexandre, Baumann, Jean-Sébastien, Martin, Fernando Ariel, Boukherroub, Rabah, Ghigo, Jean-Marc, Ortiz Mellet, Carmen, Zaitsev, Vladimi

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2015

12

Docetaxel-Loaded Nanoparticles Assembled from β-Cyclodextrin/Calixarene Giant Surfactants: Physicochemical Properties and Cytotoxic Effect in Prostate Cancer and Glioblastoma Cells

Gallego-Yerga, Laura, Posadas, Inmaculada, de la Torre, Cristina, Ruiz-Almansa, Jesús, Sansone, Francesco, Ortiz Mellet, Carmen, Casnati, Alessandro, García Fernández, José M., Ceña, Valentín

Journal:

Frontiers in Pharmacology

Année:

2017

Langue:

english

Fichier:

PDF, 4.26 MB

english, 2017

13

Trehalose-based Siamese twin amphiphiles with tunable self-assembling, DNA nanocomplexing and gene delivery properties

Carbajo-Gordillo, Ana Isabel, Rodríguez-Lavado, Julio, Jimenez Blanco, Jose Luis, Benito, Juan Manuel, Di Giorgio, Christophe, Velaz, Itziar, Tros de Ilarduya, Conchita, Ortiz Mellet, María del Carmen

Journal:

Chemical Communications

Année:

2019

Langue:

english

Fichier:

PDF, 942 KB

english, 2019

14

Tuning the Topological Landscape of DNAâCyclodextrin Nanocomplexes by Molecular Design

Neva, Tania, Gordillo, Ana I. Carbajo, Benito, Juan M., Lana, Hugo, Marcelo, Gema, Mellet, Carmen Ortiz, de Ilarduya, Conchita Tros, Mendicuti, Francisco, Garcia Fernandez, Jose M.

Journal:

Chemistry (Weinheim an der Bergstrasse, Germany)

Année:

2020

Fichier:

PDF, 2.63 MB

2020

15

S-Linked Thiomimetics of Phytoalexin-Elicitor-Active, Branched Oligosaccharides, Their Synthesis, Protein-Binding Ability and Phytoalexin-Inducing Activity

Yili Ding, Marie-Odile Contour-Galcera, Jürgen Ebel, Carmen Ortiz-Mellet, Jacques Defaye

Journal:

European Journal of Organic Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 379 KB

english, 1999

16

Cyclodextrin-Scaffolded Glycoclusters

Carmen Ortiz-Mellet, Juan M. Benito, José M. García Fernández, Ho Law, Kazimierz Chmurski, Jacques Defaye, Mary L. O'Sullivan, Hugo N. Caro

Journal:

Chemistry - A European Journal

Année:

1998

Langue:

english

Fichier:

PDF, 309 KB

english, 1998

17

Dependence of Concanavalin A Binding on Anomeric Configuration, Linkage Type, and Ligand Multiplicity for Thiourea-Bridged Mannopyranosyl–β-Cyclodextrin Conjugates

Isabelle Baussanne, Juan Manuel Benito, Carmen Ortiz Mellet, José Manuel García Fernández, Jacques Defaye

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 143 KB

english, 2001

18

Carbohydrate Microarrays

Carmen Ortiz Mellet, José M. García Fernández

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 125 KB

english, 2002

19

Cyclotrehalins: Cyclooligosaccharide Receptors Featuring a Hydrophobic Cavity

Juan M. Benito, José L. Jiménez Blanco, C. Ortiz Mellet, José M. García Fernández

Journal:

Angewandte Chemie

Année:

2002

Langue:

english

Fichier:

PDF, 88 KB

english, 2002

20

Cyclotrehalins: Cyclooligosaccharide Receptors Featuring a Hydrophobic Cavity

Juan M. Benito, José L. Jiménez Blanco, C. Ortiz Mellet, José M. García Fernández

Journal:

Angewandte Chemie

Année:

2002

Fichier:

PDF, 48 KB

2002

21

Multivalent Cyclooligosaccharides: Versatile Carbohydrate Clusters with Dual Role as Molecular Receptors and Lectin Ligands

Carmen Ortiz Mellet, Jacques Defaye, José M. García Fernández

Journal:

Chemistry - A European Journal

Année:

2002

Langue:

english

Fichier:

PDF, 309 KB

english, 2002

22

Cyclotrehalins: Cyclooligosaccharide Receptors Featuring a Hydrophobic Cavity

Juan M. Benito, José L. Jiménez Blanco, C. Ortiz Mellet, José M. García Fernández

Journal:

Angewandte Chemie International Edition

Année:

2002

Langue:

english

Fichier:

PDF, 88 KB

english, 2002

23

Cyclotrehalins: Cyclooligosaccharide Receptors Featuring a Hydrophobic Cavity

Juan M. Benito, José L. Jiménez Blanco, C. Ortiz Mellet, José M. García Fernández

Journal:

Angewandte Chemie International Edition

Année:

2002

Langue:

english

Fichier:

PDF, 43 KB

english, 2002

24

Glycosidase Inhibition with Fullerene Iminosugar Balls: A Dramatic Multivalent Effect

Philippe Compain, Camille Decroocq, Julien Iehl, Michel Holler, Damien Hazelard, Teresa Mena Barragán, Carmen Ortiz Mellet, Jean-François Nierengarten

Journal:

Angewandte Chemie

Année:

2010

Langue:

english

Fichier:

PDF, 377 KB

english, 2010

25

Glycosidase Inhibition with Fullerene Iminosugar Balls: A Dramatic Multivalent Effect

Philippe Compain, Camille Decroocq, Julien Iehl, Michel Holler, Damien Hazelard, Teresa Mena Barragán, Carmen Ortiz Mellet, Jean-François Nierengarten

Journal:

Angewandte Chemie International Edition

Année:

2010

Langue:

english

Fichier:

PDF, 397 KB

english, 2010

26

Functional Evaluation of Carbohydrate-Centred Glycoclusters by Enzyme-Linked Lectin Assay: Ligands for Concanavalin A

Maja Köhn, Juan M. Benito, Carmen Ortiz Mellet, Thisbe K. Lindhorst, José M. García Fernández

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 171 KB

english, 2004

27

6-Amino-6-deoxy-5,6-di-N-(N′-octyliminomethylidene)nojirimycin: Synthesis, Biological Evaluation, and Crystal Structure in Complex with Acid β-Glucosidase

Boris Brumshtein, Matilde Aguilar-Moncayo, M. Isabel García-Moreno, Carmen Ortiz Mellet, José M. García Fernández, Israel Silman, Yoseph Shaaltiel, David Aviezer, Joel L. Sussman, Anthony H. Futerman

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 458 KB

english, 2009

28

A Fluorescent sp2-Iminosugar With Pharmacological Chaperone Activity for Gaucher Disease: Synthesis and Intracellular Distribution Studies

Dr. Zhuo Luan , Dr. Katsumi Higaki, Dr. Matilde Aguilar-Moncayo, Linjing Li, Prof. Haruaki Ninomiya, Prof. Eiji Nanba, Prof. Kousaku Ohno, Dr. M. Isabel García-Moreno, Prof. Carmen Ortiz Mellet, Prof

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2010

29

Preorganized, Macromolecular, Gene-Delivery Systems

Carmen Ortiz Mellet, Juan M. Benito, José M. García Fernández

Journal:

Chemistry - A European Journal

Année:

2010

Langue:

english

Fichier:

PDF, 1.72 MB

english, 2010

30

Corrigendum: Preorganized, Macromolecular, Gene-Delivery Systems

Carmen Ortiz Mellet, Juan M. Benito, José M. García Fernández

Journal:

Chemistry - A European Journal

Année:

2010

Fichier:

PDF, 56 KB

2010

31

The Multivalent Effect in Glycosidase Inhibition: Probing the Influence of Architectural Parameters with Cyclodextrin-based Iminosugar Click Clusters

Camille Decroocq, Dr. David Rodríguez-Lucena, Virginie Russo, Teresa Mena Barragán, Prof. Carmen Ortiz Mellet, Prof. Philippe Compain

Journal:

Chemistry - A European Journal

Année:

2011

Langue:

english

Fichier:

PDF, 345 KB

english, 2011

32

ChemInform Abstract: Tautomeric Rearrangement of 3-Deoxy-3-thioureidoaldoses: A Novel Synthetic Route to Carbohydrate Mimics Having a Cyclic Thiourea Structure.

J. L. JIMENEZ BLANCO, C. ORTIZ MELLET, J. FUENTES, J. M. GARCIA FERNANDEZ

Journal:

Année:

1997

Fichier:

PDF, 30 KB

1997

33

ChemInform Abstract: Conformational Energetics of Sugar Thioureas and Synthesis of Glycosyl Thioureido Sugars.

J. M. GARCIA FERNANDEZ, C. ORTIZ MELLET, V. M. DIAZ PEREZ, J. L. JIMENEZ BLANCO, J. FUENTES

Journal:

Année:

1997

Fichier:

PDF, 31 KB

1997

34

ChemInform Abstract: The Thiocarbonyl Group in Carbohydrate Chemistry

J. M. GARCIA FERNANDEZ, C. ORTIZ MELLET

Journal:

Année:

1997

Fichier:

PDF, 23 KB

1997

35

ChemInform Abstract: Aza-Wittig Reaction of Sugar Isothiocyanates and Sugar Iminophosphoranes: An Easy Entry to Unsymmetrical Sugar Carbodiimides.

J. M. GARCIA FERNANDEZ, C. ORTIZ MELLET, V. M. DIAZ PEREZ, J. FUENTES, J. KOVACS, I. PINTER

Journal:

Année:

1997

Fichier:

PDF, 28 KB

1997

36

ChemInform Abstract: N-Thiocarbonyl Azasugars: A New Family of Carbohydrate Mimics with Controlled Anomeric Configuration.

J. L. JIMENEZ BLANCO, V. M. DIAZ PEREZ, C. ORTIZ MELLET, J. FUENTES, J. M. GARCIA FERNANDEZ, J. C. DIAZ ARRIBAS, F. J. CANADA

Journal:

Année:

1998

Fichier:

PDF, 33 KB

1998

37

ChemInform Abstract: Synthesis of (1 → 6)-Carbodiimide-Tethered Pseudooligosaccharides via aza-Wittig Reaction.

J. M. GARCIA FERNANDEZ, C. ORTIZ MELLET, V. M. DIAZ PEREZ, J. FUENTES, J. KOVACS, I. PINTER

Journal:

Année:

1998

Fichier:

PDF, 34 KB

1998

38

ChemInform Abstract: Synthesis of Calystegine B2 Analogues by Tandem Tautomerization-Intramolecular Glycosylation of Thioureidosugars.

J. M. GARCIA FERNANDEZ, C. ORTIZ MELLET, J. M. BENITO, J. FUENTES

Journal:

Année:

1998

Fichier:

PDF, 32 KB

1998

39

ChemInform Abstract: Synthesis and Stereoelectronic Properties of Sugar-Shaped Polyhydroxylated Hexahydropyrimidine-2-thiones.

J. L. JIMENEZ BLANCO, C. ORTIZ MELLET, J. FUENTES, J. M. GARCIA FERNANDEZ

Journal:

Année:

1999

Fichier:

PDF, 28 KB

1999

40

ChemInform Abstract: A Practical Amine-Free Synthesis of Symmetric Ureas and Thioureas by Self-Condensation of Iso(thio)cyanates.

Jose L. Jimenez Blanco, Claudio Saitz Barria, Juan M. Benito, Carmen Ortiz Mellet, Jose Fuentes, Francisco Santoyo-Gonzalez, Jose M. Garcia Fernandez

Journal:

Année:

2000

Fichier:

PDF, 28 KB

2000

41

ChemInform Abstract: Synthesis of 6,7-Dideoxy-7-isothiocyanatoheptoses: Stable Fully Unprotected Monosaccharide Isothiocyanates.

Juan Manuel Benito, Carmen Ortiz Mellet, Jose Manuel Garcia Fernandez

Journal:

Année:

2000

Fichier:

PDF, 34 KB

2000

42

ChemInform Abstract: Synthesis of Glycosyl(thio)ureido Sugars via Carbodiimides and Their Conformational Behavior in Water.

Victor Manuel Diaz Perez, Carmen Ortiz Mellet, Jose Fuentes, Jose Manuel Garcia Fernandez

Journal:

Année:

2000

Fichier:

PDF, 32 KB

2000

43

ChemInform Abstract: Synthesis and Comparative Lectin-Binding Affinity of Mannosyl-Coated β-Cyclodextrin-Dendrimer Constructs.

Isabelle Baussanne, Juan M. Benito, Carmen Ortiz Mellet, Jose M. Garcia Garcia Fernandez, Ho Law, Jacques Defaye

Journal:

Année:

2000

Fichier:

PDF, 28 KB

2000

44

ChemInform Abstract: Synthesis and Evaluation of Calystegine B2 Analogues as Glycosidase Inhibitors.

M. Isabel Garcia-Moreno, Juan M. Benito, Carmen Ortiz Mellet, Jose M. Garcia Fernandez

Journal:

Année:

2002

Fichier:

PDF, 25 KB

2002

45

ChemInform Abstract: Castanospermine-Trehazolin Hybrids: A New Family of Glycomimetics with Tunable Glycosidase Inhibitory Properties.

M. Isabel Garcia-Moreno, Paula Diaz-Perez, Carmen Ortiz Mellet, Jose M. Garcia Fernandez

Journal:

Année:

2002

Fichier:

PDF, 31 KB

2002

46

Multivalent Cyclooligosaccharides: Versatile Carbohydrate Clusters with Dual Role as Molecular Receptors and Lectin Ligands

Carmen Ortiz Mellet, Jacques Defaye, Jose M. Garcia Fernandez

Journal:

Année:

2002

Fichier:

PDF, 24 KB

2002

47

Carbohydrate Microarrays.

Carmen Ortiz Mellet, Jose M. Garcia Fernandez

Journal:

Année:

2002

Fichier:

PDF, 21 KB

2002

48

Synthesis of Sugar Oxazolines by Intramolecular Ritter-Like Reaction of D-Fructose Precursors.

Jose L. Jimenez Blanco, Enrique M. Rubio, Carmen Ortiz Mellet, Jose M. Garcia Fernandez

Journal:

Année:

2005

Fichier:

PDF, 24 KB

2005

49

ChemInform Abstract: Chemical and Enzymatic Approaches to Carbohydrate-Derived Spiroketals: Di-D-Fructose Dianhydrides (DFAs)

M. Isabel Garcia-Moreno, Juan M. Benito, Carmen Ortiz Mellet, Jose M. Garcia Fernandez

Journal:

Année:

2009

Fichier:

PDF, 11 KB

2009

50

ChemInform Abstract: (Pseudo)amide-Linked Oligosaccharide Mimetics: Molecular Recognition and Supramolecular Properties

Jose L. Jimenez Blanco, Fernando Ortega-Caballero, Carmen Ortiz Mellet, Jose M. Garcia Fernandez

Journal:

Année:

2010

Fichier:

PDF, 15 KB

2010